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Restless Legs Syndrome

Created by dave. Last edited by dave, 18 years and 45 days ago. Viewed 5,266 times. #2
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In order for you to be officially diagnosed with RLS, you must meet the criteria described in the four bullets below.

  • You have a strong urge to move your legs which you may not be able to resist. The need to move is often accompanied by uncomfortable sensations. Some words used to describe these sensations include:creeping, itching, pulling, creepy-crawly, tugging or gnawing.
  • Your RLS symptoms start or become worse when you are resting. The longer you are resting, the greater the chance the symptoms will occur and the more severe they are likely to be.
  • Your RLS symptoms get better when you move your legs. The relief can be complete or only partial but generally starts very soon after starting an activity. Relief persists as long as the motor activity continues.
  • Your RLS symptoms are worse in the evening especially when you are lying down. Activities that bother you at night do not bother you during the day.
If you do have restless legs syndrome (RLS), you are not alone. Up to 10% of the U.S. population may have this neurologic condition. Many people have a mild form of the disorder, but RLS severely affects the lives of millions of individuals.


Study: Ropinirole Improves RLS Symptoms

The drug ropinirole HCl (Requip®, GlaxoSmithKline) provides significant improvement in symptoms of restless legs syndrome, according to a study in the January issue of Mayo Clinic Proceedings.

Researchers from SleepMed of South Carolina in Columbia conducted a blinded placebo-controlled study of ropinirole HCl in 381 patients with RLS. Subjects took ropinirole HCl or placebo one to three hours before bedtime.

At 12 weeks, the average score on the International Restless Legs Scale had fallen from 22 to 8.4 in the ropinirole HCl group, and from 21.6 to 11.9 in the placebo group.

Moreover, a greater number of patients taking ropinirole HCl than placebo were “much” or “very much” improved on the Clinical Global Improvement impression score. Subjective measures of sleep disturbance, quality of life and anxiety were also significantly improved with ropinirole HCl.


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